Avian influenza: Commission strengthens preparedness with new biosecurity rules for poultry farms at risk23 August 2018 | Technical news (uncommented clippings)
Today [released August 10], the Commission adopted a Decision which lays down harmonised risk mitigation and reinforced biosecurity measures in relation to avian influenza, to prevent virus introduction by contacts with infected wild birds. This will step up preparedness and prevention ahead of the winter season. The Decision is based on EFSA's recent scientific opinion and Member States' experiences with past epidemics. It will enhance Member States' capacities to deal with crisis situations, while giving the required flexibility built on a modern risk-based approach. The measures blend perfectly with the 'One Health approach' towards diseases affecting animals and possibly humans.
First reported by Reuters, Tel Aviv, July 30:
Israel's RedHill Biopharma said on Monday it had positive safety and efficacy results from a late-stage clinical trial with its treatment for Crohn's disease called RHB-104.
The study met its primary endpoint and key secondary endpoints, demonstrating the drug's superiority over a placebo in achieving remission of the gastrointestinal disease at week 26, the company said in a statement.
"The proportion of patients meeting the primary endpoint was significantly greater in the RHB-104 group compared to placebo," RedHill said.
Patients treated with RHB-104 also experienced a statistically significant benefit in achieving early remission at week 16 and in durable remission over weeks 16-52.
RHB-104 was found to be generally safe and well tolerated, said the company, which is focused on proprietary drugs for gastrointestinal diseases.
"Many patients with Crohn’s disease do not achieve remission on current standard-of-care therapies, which are accompanied with poor side effects," said David Graham, lead investigator of the Phase III study.
"RHB-104 appears to have the potential to become a promising, new, orally administered therapy for this important debilitating disease."
RHB-104 is a proprietary, antibiotic combination therapy that is based on the hypothesis that Crohn’s disease is caused by a bacterial infection in susceptible patients called Mycobacterium avium subspecies paratuberculosis (MAP).
Comment [by Johnes.org; highlighting by TAFS]: If the final published results of this trial are consistent with the claims in this press release, it represents a final piece of evidence indicating that MAP is a cause of Crohn’s disease. This would heighten the need for veterinary medicine, animal agriculture, and relevant governmental agencies concerned with food safety to limit contamination of food and water by MAP.
Seven global food firms—Nestlé, Unilever, Ikea Food Services, Aramark, Compass Group, Elior Group, and Sodexo—have joined forces to create the Global Coalition for Animal Welfare (GCAW).
The new coalition is being called one of the world’s first global food industry-led groups focused on accelerating the development of animal welfare standards.
Factoring Chinese consumers’ risk perceptions into their willingness to pay for pork safety, environmental stewardship, and animal welfare14 December 2017 | Technical news (uncommented clippings)
65% of consumers in Beijing [74% in Shanghai] believe that animals (pigs) treated well are safer (to eat).
70% [71%] believe that animals treated well taste better.
Is the market listening?
More details, also on willingness to pay, under http://www.sciencedirect.com/science/article/pii/S0956713517304668
Ecohealth Alliance publishes updated and improved map of emerging infectious disesases (EIDs). India and eastern China light up brightly, along with southern Japan, and certain zones in western Europe and elsewhere. This is where surveillance should be focused on.
Brazil’s food safety controls for poultry and horsemeat fall short of the standards needed to ensure produce hits EU trade rules, an audit has found.
Read the entire article here: https://www.globalmeatnews.com/Article/2017/10/11/EU-Brazilian-meat-inspection-compromised
On March 24 and 25, 2017 researchers and clinicians from around the world met at Temple University in Philadelphia to discuss the current knowledge of Mycobacterium avium ssp. paratuberculosis (MAP) and its relationship to human disease. The conference was held because of shared concern that MAP is a zoonotic bacterium that poses a threat not only to animal health but also human health.
Read the full paper here: https://www.frontiersin.org/articles/10.3389/fpubh.2017.00208/full
TAFS publishes short summary of H5N8 outbreaks in Europe.
It may be downloaded here: http://tafsforum.org/influenza.html
TAFS member Prof. Adriano Aguzzi explains latest research on how the flexible tail of the prion protein poisons brain cells.
Watch the video here.
New paper: Bluetongue Disease Risk Assessment Based on Observed and Projected Culicoides obsoletus spp. Vector Densities29 April 2013 | Technical news (uncommented clippings)
TAFS members Katharina Brugger and Franz Rubel have published a new paper entitled "Bluetongue Disease Risk Assessment Based on Observed and Projected Culicoides obsoletus spp. Vector Densities". Congratulations!
A news article published by NBC News reports on suspected toxicological effects of chemicals used by the petrol industry for 'fracking'. Available data are insufficient for proper risk assessment. The issue involves livestock, humans, and the environment and hence calls for a 'One Health' approach.
Please see the summary article 'The Prion Puzzle' on BSE and other prion diseases by our member Professor Adriano Aguzzi on the website of 'Project Syndicate'.
A national programme to eradicate Johne's Disease (Paratuberculosis) will start in Ireland next January.
The disease is said to be 'a major cause for concern for dairy processors supplying product into the infant formula market', but beef processors are also believed to be 'anxious to tackle the issue'.
In a commentary paper published this month, the Council for Agricultural Science and Technology (CAST) discusses "The Direct Relationship between Animal Health and Food Safety Outcomes".
Parker et al. have published the description on an "Algorithm for Assessing the Risk to Food Safety Posed by a New Animal Disease". Their approach is strikingly similar to the one taken regularly by TAFS to assess food safety risks.
Parker, E. M., Jenson, I., Jordan, D. and Ward, M. P. (2012), Development of an Algorithm for Assessing the Risk to Food Safety Posed by a New Animal Disease. Zoonoses and Public Health, 59: 184–192. doi: 10.1111/j.1863-2378.2011.01431.x
USDA announced the identification of the fourth case of BSE in the USA. The cow was found dead on a dairy farm in central California and tested for BSE before the carcass would be released for rendering. Initial test results were inconclusive, but retesting by USDA's National Veterinary Services Laboratories in Ames, Iowa, using immunohistochemistry and western blots confirmed atypical BSE.
Dr. Anthony A. Frank, president of Colorado State University, called for 'common ground', addressing participants of the NIAA (National Institute for Animal Agriculture) annual conference in Denver, Colorado (March 26 - 29, 2012).
The TAFS forum delivers exactly that.
After a recent report about a 'probable variant Creutzfeldt-Jakob disease' case, the EUROCJD group replies in a public letter why it considers the diagnosis 'unlikely'. The group states that 'the diagnosis of vCJD cannot be regarded as correct unless there is neuropathological verification of this diagnosis'.
Fish and spices the most common sources
Read full article here.
A new synopsis in EID by Saunders et al. summarizes 'Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease'.
Long awaited, a key reference in our 'Recommended Risk Management Plan for Paratuberculosis' has finally become available online. You can find the paper 'Assessment of Sources of Exposure for Mycobacterium avium subsp. paratuberculosis in Food and Water' by Mihajlovic et al. in Int. food risk anal. j., 2011, Vol. 1, No. 2, 1-22, here. The paper represents another compilation of studies on MAP in food and water.
Cows have best friends and become stressed if they are separated, according to a scientist. Read the full article under the hyperlink above.
Wishing all TAFS forum members and everybody following our newsletter that you will have plenty of opportunity to see your best friends in 2012.
High levels of aflatoxin M1 have been found in a batch of milk before release for sales by China Mengniu Dairy Group and created a new scare, following the contamination of milk with melamine in 2008.
T. Seuberlich et al. (including our member D. Heim) report about the finding of a novel prion protein in two BSE-affected cattle. In April and May 2011, two cows were found BSE-positive by Western Blotting. Their PrPres phenotypes falls in none of the three previously described categories, C-BSE, H-BSE or L-BSE.
The significance of this finding is unclear.
The US National Advisory Committee on Microbiological Criteria for Foods has published its review 'Assessment of Food as a Source of Exposure to Mycobacterium avium subspecies paratuberculosis (MAP)'.
At its 78th General Session, the World Organisation for Animal Health OIE has newly recognised India and Peru as having a 'negligible' BSE risk.
The Republic of Korea and Panama were added to the list of countries with 'controlled' BSE risk.
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